Cancer research in an era when epigenetics is no longer “epi”—challenges and opportunities
نویسنده
چکیده
Oncology in South China, Sir YK Pao Center for Cancer and Li Ka Shing Institute of Health Sciences, Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong and CUHK -Shenzhen Research Institute. Qian Tao, Rm 315, Cancer Center, PWH, Department of Clinical Oncology, The Chinese University of Hong Kong, Shatin, Hong Kong. Tel: +852鄄 2632鄄 1340, Fax: +852鄄 2648鄄 8842; Email: qtao@ cuhk.edu.hk. 10.5732/cjc.012.10300
منابع مشابه
First Barcelona Conference on Epigenetics and Cancer
The Barcelona Conference on Epigenetics and Cancer (BCEC) entitled "Challenges, opportunities and perspectives" took place November 21-22, 2013 in Barcelona. The 2013 BCEC is the first edition of a series of annual conferences jointly organized by five leading research centers in Barcelona. These centers are the Institute of Predictive and Personalized Medicine of Cancer (IMPPC), the Biomedical...
متن کاملEpigenetic research in cancer epidemiology: trends, opportunities, and challenges.
Epigenetics is emerging as an important field in cancer epidemiology that promises to provide insights into gene regulation and facilitate cancer control throughout the cancer care continuum. Increasingly, investigators are incorporating epigenetic analysis into the studies of etiology and outcomes. To understand current progress and trends in the inclusion of epigenetics in cancer epidemiology...
متن کاملExploiting tumor vulnerabilities: epigenetics, cancer metabolism and the mTOR pathway in the era of personalized medicine.
Patient stratification according to drug responses, together with the discovery of novel antitumor targets, is leading to a new era of personalized cancer treatments. With the aim of identifying emerging pathways and the challenges faced by clinicians during clinical trials, the IDIBELL Cancer Conference on Personalized Cancer Medicine took place in Barcelona on December 3-4, 2012. This confere...
متن کاملThe Role of Epigenetics in Cancer Drug Resistance
Cancer is caused by aberrant genetic and epigenetic changes in genes expression. DNA methylation, histone modification, and microRNAs gene deregulation are the most known epigenetic changes in different stages of cancer. Since every tumor has its own specific epigenome, any abnormal pattern is a potential biomarker for classification of different types of tumors. Despite, tumorigenesis, abnorma...
متن کاملEpigenetics in diagnosis of colorectal cancer
Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the...
متن کامل